Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Gobs_4983TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: kra:Krad_4198 exodeoxyribonuclease III Xth. (264 aa)    
Predicted Functional Partners:
Gobs_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.864
Gobs_0374
KEGG: hypothetical protein.
  
    0.771
Gobs_2989
PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: sen:SACE_5237 pseudouridylate synthase ribosomal large subunit; Belongs to the pseudouridine synthase RsuA family.
  
    0.771
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
    
 
 0.754
Gobs_5069
PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: sen:SACE_7353 endonuclease IV.
    
 
 0.754
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 0.703
Gobs_1012
Transcriptional regulator, AraC family; PFAM: Ada metal-binding domain protein; AlkA domain protein; HhH-GPD family protein; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; HhH-GPD family protein; KEGG: stp:Strop_3783 alcohol dehydrogenase.
   
 0.692
Gobs_0756
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; iron- sulfur cluster loop; KEGG: stp:Strop_0568 DNA-cytosine methyltransferase.
   
 0.672
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.670
Gobs_3560
TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein; KEGG: sma:SAV_4172 hypothetical protein.
  
 0.658
Your Current Organism:
Geodermatophilus obscurus
NCBI taxonomy Id: 526225
Other names: G. obscurus DSM 43160, Geodermatophilus obscurus ATCC 25078, Geodermatophilus obscurus DSM 43160, Geodermatophilus obscurus IFO 13315, Geodermatophilus obscurus JCM 3152, Geodermatophilus obscurus NBRC 13315, Geodermatophilus obscurus NRRL B-3577, Geodermatophilus obscurus VKM Ac-658, Geodermatophilus obscurus str. DSM 43160, Geodermatophilus obscurus strain DSM 43160
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