STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gbro_0536KEGG: bgl:bglu_1g01500 hypothetical protein. (304 aa)    
Predicted Functional Partners:
Gbro_0534
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: bgl:bglu_1g01510 DNA cytosine methyltransferase M.NgoMIII.
 
  
 0.768
Gbro_0537
Hypothetical protein.
       0.540
Gbro_1453
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ecp:ECP_4572 modification methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
  
 0.488
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.467
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.466
Gbro_0825
PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: gme:Gmet_3140 DNA adenine methylase.
  
  
 0.421
Gbro_0538
KEGG: ppg:PputGB1_0529 hypothetical protein.
       0.419
Your Current Organism:
Gordonia bronchialis
NCBI taxonomy Id: 526226
Other names: G. bronchialis DSM 43247, Gordonia bronchialis ATCC 25592, Gordonia bronchialis CCUG 20989, Gordonia bronchialis CCUG 34956, Gordonia bronchialis CIP 100847, Gordonia bronchialis DSM 43247, Gordonia bronchialis IFO 6047, Gordonia bronchialis JCM 3198, Gordonia bronchialis JCM 3231, Gordonia bronchialis LMG 5355, Gordonia bronchialis NBRC 16047, Gordonia bronchialis NCTC 10667, Gordonia bronchialis VKM Ac-956, Gordonia bronchialis str. DSM 43247, Gordonia bronchialis str. Tsukamura 3410, Gordonia bronchialis strain DSM 43247
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