STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ornExonuclease RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (194 aa)    
Predicted Functional Partners:
Gbro_2154
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: gme:Gmet_1588 phosphoesterase, RecJ-like.
     
 0.626
Gbro_2225
KEGG: ypy:YPK_1925 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; protein of unknown function DUF1605; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
 
  
 0.622
Gbro_2013
PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: dar:Daro_4068 hypothetical protein.
       0.621
Gbro_4840
KEGG: hypothetical protein; TIGRFAM: tRNA adenylyltransferase; metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
   
 0.585
Gbro_2058
Ribonuclease, Rne/Rng family; KEGG: eba:ebA3964 ribonuclease G (RNase G); TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; translation initiation factor IF-2 domain protein.
  
  
 0.555
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
      
 0.552
rnj
Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
      
 0.539
Gbro_2014
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: abb:ABBFA_001631 short chain dehydrogenase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.534
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
  
 0.529
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.519
Your Current Organism:
Gordonia bronchialis
NCBI taxonomy Id: 526226
Other names: G. bronchialis DSM 43247, Gordonia bronchialis ATCC 25592, Gordonia bronchialis CCUG 20989, Gordonia bronchialis CCUG 34956, Gordonia bronchialis CIP 100847, Gordonia bronchialis DSM 43247, Gordonia bronchialis IFO 6047, Gordonia bronchialis JCM 3198, Gordonia bronchialis JCM 3231, Gordonia bronchialis LMG 5355, Gordonia bronchialis NBRC 16047, Gordonia bronchialis NCTC 10667, Gordonia bronchialis VKM Ac-956, Gordonia bronchialis str. DSM 43247, Gordonia bronchialis str. Tsukamura 3410, Gordonia bronchialis strain DSM 43247
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.