STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)    
Predicted Functional Partners:
Gbro_4398
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
Gbro_0083
PFAM: AMP-dependent synthetase and ligase; KEGG: rlt:Rleg2_6131 AMP-dependent synthetase and ligase.
  
 
 0.968
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.966
Gbro_0763
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: bxe:Bxe_A1651 isocitrate lyase.
   
  
 0.954
Gbro_2788
PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: bbt:BBta_0892 pyruvate dehydrogenase; Belongs to the TPP enzyme family.
    
 0.954
Gbro_0958
PFAM: Aldehyde Dehydrogenase; KEGG: bur:Bcep18194_B1170 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.920
Gbro_1599
PFAM: Aldehyde Dehydrogenase; KEGG: mpt:Mpe_A2577 aldehyde dehydrogenase.
  
 
 0.920
Gbro_3847
PFAM: Aldehyde Dehydrogenase; KEGG: rpi:Rpic_1338 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.920
Gbro_4523
Lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: hypothetical protein; K00101 L-lactate dehydrogenase (cytochrome).
    
 0.912
Gbro_2075
PFAM: acylphosphatase; KEGG: ecg:E2348C_0954 predicted acylphosphatase.
     
 0.911
Your Current Organism:
Gordonia bronchialis
NCBI taxonomy Id: 526226
Other names: G. bronchialis DSM 43247, Gordonia bronchialis ATCC 25592, Gordonia bronchialis CCUG 20989, Gordonia bronchialis CCUG 34956, Gordonia bronchialis CIP 100847, Gordonia bronchialis DSM 43247, Gordonia bronchialis IFO 6047, Gordonia bronchialis JCM 3198, Gordonia bronchialis JCM 3231, Gordonia bronchialis LMG 5355, Gordonia bronchialis NBRC 16047, Gordonia bronchialis NCTC 10667, Gordonia bronchialis VKM Ac-956, Gordonia bronchialis str. DSM 43247, Gordonia bronchialis str. Tsukamura 3410, Gordonia bronchialis strain DSM 43247
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