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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gbro_4635PFAM: sigma-70 region 4 domain protein; KEGG: ank:AnaeK_1887 putative RNA polymerase, sigma 70 family subunit. (289 aa)    
Predicted Functional Partners:
Gbro_4099
PFAM: transcription activator effector binding; regulatory protein MerR; SMART: regulatory protein MerR; KEGG: cvi:CV_4236 MerR family transcriptional regulator.
  
 
 0.781
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.666
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.632
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.604
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.589
Gbro_0970
PFAM: transcription factor CarD; KEGG: pca:Pcar_0104 putative transcriptional regulator.
   
 
 0.555
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.541
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
    
 
 0.531
Gbro_4636
Citrate (pro-3S)-lyase; PFAM: HpcH/HpaI aldolase; KEGG: sfu:Sfum_2561 citrate (pro-3S)-lyase; Belongs to the HpcH/HpaI aldolase family.
       0.515
Gbro_4440
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SMART: cyclic nucleotide-binding; KEGG: afw:Anae109_3313 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.443
Your Current Organism:
Gordonia bronchialis
NCBI taxonomy Id: 526226
Other names: G. bronchialis DSM 43247, Gordonia bronchialis ATCC 25592, Gordonia bronchialis CCUG 20989, Gordonia bronchialis CCUG 34956, Gordonia bronchialis CIP 100847, Gordonia bronchialis DSM 43247, Gordonia bronchialis IFO 6047, Gordonia bronchialis JCM 3198, Gordonia bronchialis JCM 3231, Gordonia bronchialis LMG 5355, Gordonia bronchialis NBRC 16047, Gordonia bronchialis NCTC 10667, Gordonia bronchialis VKM Ac-956, Gordonia bronchialis str. DSM 43247, Gordonia bronchialis str. Tsukamura 3410, Gordonia bronchialis strain DSM 43247
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