STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH62007.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR016040:IPR002198:IPR004360:IPR002347; KEGG: rxy:Rxyl_2616 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: C1XS17 Putative uncharacterized protein; PFAM: short chain dehydrogenase; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (365 aa)    
Predicted Functional Partners:
ADH62008.1
Queuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
     0.933
ADH62006.1
KEGG: mxa:MXAN_6319 phospholipase D family protein; SPTR: C1XS18 Putative uncharacterized protein.
       0.773
ADH64415.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.773
ADH64413.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: ter:Tery_4543 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XP79 Putative uncharacterized protein; PFAM: short chain dehydrogenase.
  
   0.753
ADH63727.1
Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR011966:IPR016161:IPR015590:IPR016162:IPR 002539; KEGG: dge:Dgeo_1913 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; SPTR: C1XT04 Phenylacetic acid degradation protein paaN; TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN.
  
 0.740
ADH62005.1
Ankyrin; InterPro IPR020683:IPR002110; KEGG: bai:BAA_4614 ankyrin repeat domain protein; PFAM: Ankyrin; SMART: Ankyrin; SPTR: C1XS19 Ankyrin repeat-containing protein; PFAM: Ankyrin repeat.
  
 0.736
ADH62027.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR016040:IPR002198:IPR002347; KEGG: rxy:Rxyl_2474 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XRZ6 Putative uncharacterized protein; PFAM: short chain dehydrogenase.
  
   0.735
nuoI
NADH-quinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.727
ADH62659.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
 0.711
ADH63676.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR016040:IPR013328:IPR006176:IPR006108:IPR 001753:IPR008927; KEGG: ttj:TTHA0890 putative 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: C1XTA0 3-hydroxyacyl-CoA dehydrogenase; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.687
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.