STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (496 aa)    
Predicted Functional Partners:
ADH64663.1
FAD dependent oxidoreductase; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR000447:IPR006076; KEGG: gbm:Gbem_3375 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: C1XTT3 Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 0.996
ADH63990.1
Mov34/MPN/PAD-1 family protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: ttj:TTHA1497 hypothetical protein; SMART: Mov34/MPN/PAD-1 family protein; SPTR: C1XQI1 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.
   
 0.992
ADH64988.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425:IPR012269; KEGG: pcu:pc0796 putative tonoplast intrinsic protein (aquaporin); PFAM: major intrinsic protein; SPTR: C1XVE6 MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.957
ADH63417.1
Protein of unknown function DUF205; COGs: COG0344 membrane protein; InterPro IPR003811; KEGG: ttj:TTHA0808 hypothetical protein; PFAM: protein of unknown function DUF205; SPTR: C1XUN9 Predicted membrane protein, COG0344; PFAM: Domain of unknown function (DUF205); TIGRFAM: conserved hypothetical integral membrane protein TIGR00023; Belongs to the PlsY family.
     
 0.910
plsY-2
Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.910
ADH62005.1
Ankyrin; InterPro IPR020683:IPR002110; KEGG: bai:BAA_4614 ankyrin repeat domain protein; PFAM: Ankyrin; SMART: Ankyrin; SPTR: C1XS19 Ankyrin repeat-containing protein; PFAM: Ankyrin repeat.
   
 0.802
ADH65012.1
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129:IPR017946:IPR000909; KEGG: ttj:TTHB141 putative glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: C1XVB9 Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
 
  
 0.762
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.686
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  0.652
ADH64760.1
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: tth:TTC1583 nucleoside triphosphate pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: C1XVA0 MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
      0.645
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.