STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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ADH62956.1Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789:IPR011991:IPR011006; KEGG: sti:Sthe_1552 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: C1XXG0 Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family. (211 aa)    
Predicted Functional Partners:
ADH64691.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR000014:IPR003018:IPR003594:IPR013767:IPR 011712:IPR005467; KEGG: rca:Rcas_4226 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; GAF domain protein; PAS fold domain protein; PRIAM: Histidine kinase; SMART: GAF domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein; SPTR: C1XTQ5 PAS domain S-box protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase; GAF domain; Histidi [...]
 
 0.946
ADH62955.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR003594:IPR017205:IPR011712:IPR005467:IPR 004358; KEGG: sti:Sthe_1551 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; SPTR: C1XXG1 Signal transduction histidine kinase, COG4585; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.944
ADH62011.1
COGs: COG4585 Signal transduction histidine kinase; InterProIPR003594:IPR003018:IPR011712:IPR005467:IPR 004358; KEGG: bcl:ABC3141 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: C1XS12 Histidine kinase with GAF domain; PFAM: Histidine kinase; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.905
ADH64550.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358:IPR011712; KEGG: ttj:TTHA1181 sensor histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; SPTR: C1XU56 Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 0.869
ADH63724.1
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR001789:IPR 005467:IPR004105:IPR004358:IPR011006:IPR009082; KEGG: dra:DR_A0355 CheA-related protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: C1XT07 Chemotaxis protein histidine kinase-lik [...]
 
 
 0.574
ADH62634.1
Transcriptional regulator, LuxR family; COGs: COG3903 ATPase; InterProIPR000792:IPR011991:IPR013026:IPR011990:IPR 011717:IPR016032; KEGG: rha:RHA1_ro02716 protein kinase/LuxR family transcriptional regulator; PFAM: regulatory protein LuxR; Tetratricopeptide TPR_4; SMART: regulatory protein LuxR; SPTR: C1XW77 Predicted ATPase, COG3903; PFAM: Bacterial regulatory proteins, luxR family.
  
  
 0.538
ADH63723.1
COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dra:DR_A0353 methyl-accepting chemotaxis-related protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: C1XT08 Methyl-accepting chemotaxis protein; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain.
 
 
 0.496
ADH64398.1
COGs: COG3629 DNA-binding transcriptional activator of the SARP family; InterProIPR013105:IPR019734:IPR005158:IPR001867:IPR 013026:IPR001440:IPR011990; KEGG: rca:Rcas_3701 SARP family transcriptional regulator; PFAM: transcriptional activator domain; Tetratricopeptide TPR_2 repeat protein; transcriptional regulator domain protein; TPR repeat-containing protein; SPTR: C1XP95 DNA-binding transcriptional activator of the SARP family; PFAM: Bacterial transcriptional activator domain; IstB-like ATP binding protein.
  
 
 0.453
ADH63586.1
COGs: COG0069 Glutamate synthase domain 2; InterProIPR006982:IPR002489:IPR002932:IPR017932:IPR 000583; KEGG: ttj:TTHA1468 glutamate synthase, large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: C1XYW8 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.425
ADH63719.1
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: dra:DR_A0350 response regulator PilH, putative; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: C1XT12 Response regulator containing a CheY-like receiver domain and a GGDEF domain; PFAM: Response regulator receiver domain.
 
 
 0.412
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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