STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH63134.1CRISPR-associated protein Cas2; InterPro IPR010152; KEGG: ttj:TTHB194 hypothetical protein; PFAM: CRISPR-associated protein Cas2; SPTR: C1XG05 CRISPR-associated protein, Cas2 family; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated protein Cas2, E. coli subfamily. (125 aa)    
Predicted Functional Partners:
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.995
ADH63131.1
InterPro IPR010147:IPR013422; KEGG: ppd:Ppro_2339 CRISPR-associated Cas5 family protein; PFAM: CRISPR-associated protein CT1976; SPTR: C1XXW3 CRISPR-associated protein, Cas5e family; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5, Ecoli subtype.
 
  
 0.970
ADH63132.1
InterPro IPR010179; KEGG: avn:Avin_17220 CRISPR-associated protein, CT1974; PFAM: CRISPR-associated protein CT1974; SPTR: C1XG03 CRISPR-associated protein, Cse3 family; TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family.
 
  
 0.969
ADH63130.1
CRISPR-associated protein, Cse4 family; InterPro IPR018506:IPR010148; KEGG: avn:Avin_17200 CRISPR-associated protein, CT1975; PFAM: CRISPR-associated protein CT1975; SPTR: C1XG01 CRISPR-associated protein, Cse4 family; TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family.
 
  
 0.968
ADH63127.1
CRISPR-associated protein, Cse1 family; InterPro IPR013381; KEGG: ttj:TTHB188 hypothetical protein; PFAM: CRISPR-associated protein Cse1; SPTR: C1XYH9 CRISPR-associated protein, Cse1 family; TIGRFAM: CRISPR-associated protein, Cse1 family; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family.
 
   
 0.963
ADH63128.1
InterPro IPR013382; KEGG: ppd:Ppro_2341 CRISPR-associated CSE2 family protein; PFAM: CRISPR-associated protein Cse2; SPTR: C1XYH7 CRISPR-associated protein, Cse2 family; TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR-associated protein, Cse2 family.
 
   
 0.950
ADH63125.1
CRISPR-associated helicase Cas3; COGs: COG1203 helicase; InterPro IPR001650:IPR014021:IPR006474:IPR014001; KEGG: dge:Dgeo_2629 CRISPR-associated helicase Cas3 family protein protein; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C1XFZ7 CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: HD domain; Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3.
 
  
 0.922
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.897
ADH63129.1
KEGG: ttj:TTHA0268 hypothetical protein; SPTR: C1XYH6 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2939).
       0.757
ADH63126.1
KEGG: hypothetical protein; K02355 elongation factor EF-G; SPTR: C1XYI0 Putative uncharacterized protein.
       0.593
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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