STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH63189.1COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR014273:IPR019818:IPR001804; KEGG: gwc:GWCH70_0444 isocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: C1XXQ4 Isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase; isocitrate dehydrogenase, NADP-dependent, prokaryotic type. (480 aa)    
Predicted Functional Partners:
ADH63998.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.952
ADH63567.1
Isocitrate dehydrogenase, NADP-dependent; COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR001804:IPR004439:IPR019818; KEGG: rmr:Rmar_1401 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; SPTR: C1XU73 Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
 
0.950
ADH63818.1
COGs: COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1); InterPro IPR011603:IPR005475:IPR001017; KEGG: ttj:TTHA0289 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase central region; dehydrogenase E1 component; PRIAM: Oxoglutarate dehydrogenase (succinyl-transferring); SMART: Transketolase central region; SPTR: C1XT57 2-oxoglutarate dehydrogenase E1 component; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Dehydrogenase E1 component; Transketolase, pyrimidine binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component.
   
 0.921
ADH63586.1
COGs: COG0069 Glutamate synthase domain 2; InterProIPR006982:IPR002489:IPR002932:IPR017932:IPR 000583; KEGG: ttj:TTHA1468 glutamate synthase, large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: C1XYW8 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 0.920
ADH64059.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016162; KEGG: ddr:Deide_16070 putative succinate-semialdehyde dehydrogenase (NAD(P)(+)); PFAM: Aldehyde Dehydrogenase; PRIAM: Succinate-semialdehyde dehydrogenase; SPTR: C1XQA8 Succinate semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase.
   
 0.828
argH
COGs: COG0165 Argininosuccinate lyase; InterProIPR020557:IPR008948:IPR000362:IPR009049:IPR 003031; KEGG: ttj:TTHA0283 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPT6 Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
  
 
 0.826
ADH64316.1
Fumarate lyase; COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362:IPR008948:IPR020557:IPR003031; KEGG: ddr:Deide_1p00670 putative argininosuccinate lyase; PFAM: fumarate lyase; SPTR: C1XPI0 Argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
  
 
 0.826
ADH63395.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterProIPR006095:IPR016040:IPR006097:IPR006096:IPR 014362; KEGG: ttj:TTHA1577 putative NAD-dependent glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NAD(P)(+)); SPTR: C1XUR6 Glutamate dehydrogenase (NADP); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.822
ADH63396.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterProIPR016040:IPR014362:IPR006096:IPR006095:IPR 006097; KEGG: tth:TTC1211 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SMART: Glu/Leu/Phe/Val dehydrogenase; SPTR: C1XUR5 Glutamate dehydrogenase (NADP); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.822
ADH64856.1
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II.
   
 
 0.812
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.