STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH63425.1Modification methylase, HemK family; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR004556:IPR007848:IPR002052; KEGG: ttj:TTHA0441 HemK family methyltransferase; PFAM: methyltransferase small; SPTR: C1XUN1 Putative methylase of HemK family; TIGRFAM: modification methylase, HemK family; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific. (288 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.988
ADH62342.1
KEGG: tth:TTC1121 hypothetical protein; SPTR: C1XR12 Putative uncharacterized protein; PFAM: eRF1 domain 3.
    
 0.928
ADH63342.1
H+transporting two-sector ATPase C subunit; InterPro IPR002379; KEGG: ttj:TTHA1277 V-type ATP synthase, subunit K; PFAM: H+transporting two-sector ATPase C subunit; SPTR: C1XVV2 ATP synthase subunit C; PFAM: ATP synthase subunit C.
  
   0.742
ADH62120.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
  
 0.729
tilS
tRNA(Ile)-lysidine synthetase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.683
ADH63424.1
Inositol monophosphatase; COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR020550:IPR020583:IPR000760; KEGG: tth:TTC1928 myo-inositol-1(or 4)-monophosphatase; PFAM: inositol monophosphatase; SPTR: C1XUN2 Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; PFAM: Inositol monophosphatase family.
  
    0.680
ADH63426.1
Single-stranded nucleic acid binding R3H domain protein; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ttj:TTHA0442 DNA/RNA-binding protein (Jag-related protein); PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; SPTR: C1XUN0 Predicted RNA-binding protein; PFAM: R3H domain.
       0.656
ADH62548.1
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 
 0.650
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.626
yidC
Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
    0.594
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.