node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADH63709.1 | ADH63710.1 | Mesil_1832 | Mesil_1833 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Protein of unknown function DUF752; COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: ttj:TTHA0878 hypothetical protein; PFAM: protein of unknown function DUF752; SPTR: C1XJQ1 Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF752). | 0.666 |
ADH63709.1 | ADH63963.1 | Mesil_1832 | Mesil_2091 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | 0.808 |
ADH63709.1 | ADH64856.1 | Mesil_1832 | Mesil_3018 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. | 0.915 |
ADH63709.1 | dnaK | Mesil_1832 | Mesil_0428 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.594 |
ADH63709.1 | hisC | Mesil_1832 | Mesil_2619 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR001917:IPR015424:IPR005861:IPR 004839; KEGG: ttj:TTHA0428 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XP21 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.906 |
ADH63709.1 | kynA | Mesil_1832 | Mesil_2680 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Tryptophan 2,3-dioxygenase apoenzyme; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.900 |
ADH63709.1 | kynB | Mesil_1832 | Mesil_0987 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.900 |
ADH63709.1 | nnrD | Mesil_1832 | Mesil_0951 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.565 |
ADH63709.1 | trpA | Mesil_1832 | Mesil_1839 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.802 |
ADH63709.1 | trpB | Mesil_1832 | Mesil_1838 | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.800 |
ADH63710.1 | ADH63709.1 | Mesil_1833 | Mesil_1832 | Protein of unknown function DUF752; COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: ttj:TTHA0878 hypothetical protein; PFAM: protein of unknown function DUF752; SPTR: C1XJQ1 Uncharacterized conserved protein; PFAM: Protein of unknown function (DUF752). | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | 0.666 |
ADH63963.1 | ADH63709.1 | Mesil_2091 | Mesil_1832 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | 0.808 |
ADH63963.1 | ADH64856.1 | Mesil_2091 | Mesil_3018 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. | 0.990 |
ADH63963.1 | hisC | Mesil_2091 | Mesil_2619 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR001917:IPR015424:IPR005861:IPR 004839; KEGG: ttj:TTHA0428 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XP21 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.942 |
ADH63963.1 | trpA | Mesil_2091 | Mesil_1839 | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.473 |
ADH64856.1 | ADH63709.1 | Mesil_3018 | Mesil_1832 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | 0.915 |
ADH64856.1 | ADH63963.1 | Mesil_3018 | Mesil_2091 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. | Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: ttj:TTHA1104 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: C1XQL1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain. | 0.990 |
ADH64856.1 | hisC | Mesil_3018 | Mesil_2619 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR001176:IPR004838:IPR 015421; KEGG: tth:TTC1960 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XV01 Aspartate/tyrosine/aromatic aminotransferase; PFAM: Aminotransferase class I and II. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR001917:IPR015424:IPR005861:IPR 004839; KEGG: ttj:TTHA0428 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XP21 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.918 |
dnaK | ADH63709.1 | Mesil_0428 | Mesil_1832 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | 0.594 |
hisC | ADH63709.1 | Mesil_2619 | Mesil_1832 | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR015421:IPR001917:IPR015424:IPR005861:IPR 004839; KEGG: ttj:TTHA0428 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: C1XP21 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | COGs: COG0076 Glutamate decarboxylase and related PLP-dependent protein; InterProIPR015424:IPR015422:IPR002129:IPR010977:IPR 015421; KEGG: chl:Chy400_3078 aromatic-L-amino-acid decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; SPTR: C1XT64 PLP-dependent enzyme, glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase conserved domain. | 0.906 |