STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH63955.1Cobalamin synthesis protein P47K; COGs: COG0523 Putative GTPase (G3E family); InterPro IPR011629:IPR003495; KEGG: ddr:Deide_00450 putative cobalamin synthesis protein, P47K; PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; SMART: cobalamin synthesis CobW domain protein; SPTR: C1XQL9 Predicted GTPase, G3E family; PFAM: CobW/HypB/UreG, nucleotide-binding domain; Cobalamin synthesis protein cobW C-terminal domain. (311 aa)    
Predicted Functional Partners:
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
 
 0.758
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.695
rpmB
Ribosomal protein L28; InterPro IPR001383; KEGG: ttj:TTHA0042 50S ribosomal protein L28; SPTR: C1XV04 LSU ribosomal protein L28P; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.671
ADH63873.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129:IPR006127:IPR006128; KEGG: ttj:TTHA0596 ABC transporter solute-binding protein; PFAM: periplasmic solute binding protein; SPTR: C1XQV2 ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.657
ADH63956.1
YibE/F family protein; COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: tth:TTC0924 hypothetical protein; PFAM: YibE/F family protein; SPTR: C1XQL8 Predicted multitransmembrane protein; PFAM: YibE/F-like protein.
       0.648
ADH62604.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006129:IPR006127:IPR006128; KEGG: ddr:Deide_3p02720 putative metal ion ABC transporter, periplasmic component/surface adhesin; PFAM: periplasmic solute binding protein; SPTR: C1XWB0 ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.621
hisI
phosphoribosyl-ATP diphosphatase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179:IPR002496; KEGG: ttj:TTHA1445 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; SPTR: C1XQD4 Phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; b [...]
     
 0.582
rpmG
Ribosomal protein L33; InterPro IPR001705:IPR018264; KEGG: ttj:TTHA0250 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: C1XZ54 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.565
ADH63822.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.539
ADH63957.1
G8 domain-containing protein; InterPro IPR019316; KEGG: chl:Chy400_1569 blue (type 1) copper domain protein; PFAM: G8 domain; SPTR: C1XQL7 G8 domain-containing protein; PFAM: G8 domain.
 
     0.517
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.