STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADH64088.1Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814:IPR015424:IPR015421; KEGG: tth:TTC0553 ornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: C1XK59 Ornithine/acetylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (411 aa)    
Predicted Functional Partners:
ADH64152.1
Arginase/agmatinase/formiminoglutamase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR020855; KEGG: dge:Dgeo_2732 arginase/agmatinase/formiminoglutamase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: C1XQ06 Arginase family hydrolase, arginase/agmainase/formiminoglutamate hydrolase; PFAM: Arginase family; TIGRFAM: agmatinase; Belongs to the arginase family.
  
 0.936
ADH64269.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016161:IPR015590:IPR016162:IPR016160; KEGG: aha:AHA_3818 gamma-aminobutyraldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; PRIAM: Aminobutyraldehyde dehydrogenase; SPTR: C1XPM9 NAD-dependent aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: 1-pyrroline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.922
speE
Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
     
 0.913
ADH62218.1
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: ttj:TTHA1901 carbon-nitrogen hydrolase family protein; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: C1XRE1 Predicted amidohydrolase; PFAM: Carbon-nitrogen hydrolase.
    
  0.903
ADH64309.1
N-carbamoylputrescine amidase; COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR017755; KEGG: dra:DR_2535 hydrolase, putative; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: C1XPI7 N-carbamoylputrescine amidase; TIGRFAM: N-carbamoylputrescine amidase; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: N-carbamoylputrescine amidase.
    
  0.903
ADH64917.1
FAD dependent oxidoreductase; InterPro IPR017909:IPR006311:IPR006076; KEGG: aba:Acid345_1633 hypothetical protein; PFAM: FAD dependent oxidoreductase; SPTR: C1XUT4 FAD dependent oxidoreductase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
   
 
  0.902
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.859
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: ttj:TTHA0284 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: C1XPT4 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.821
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
  
 0.808
ADH64654.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
  
 0.772
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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