STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH64184.1TPR repeat-containing protein; COGs: COG2909 ATP-dependent transcriptional regulator protein; InterPro IPR001440:IPR011990:IPR019734:IPR013026; KEGG: tth:TTC0344 hypothetical protein; PFAM: TPR repeat-containing protein; SPTR: C1XPW9 ATP-dependent transcriptional regulator; PFAM: Tetratricopeptide repeat. (920 aa)    
Predicted Functional Partners:
ADH64189.1
Extracellular ligand-binding receptor; COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: tth:TTC0338 leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: C1XPW4 ABC-type branched-chain amino acid transport system, periplasmic component; PFAM: Receptor family ligand binding region.
 
     0.828
ADH64583.1
COGs: COG3307 Lipid A core - O-antigen ligase; InterPro IPR007016; KEGG: dae:Dtox_0160 YD repeat protein; PFAM: O-antigen polymerase; SPTR: C1XU21 Lipid A core-O-antigen ligase-like enyme; PFAM: O-Antigen ligase.
  
     0.771
ADH62617.1
CRISPR-associated RAMP protein, Csm4 family; COGs: COG1567 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR005510; KEGG: ttj:TTHB150 hypothetical protein; PFAM: protein of unknown function DUF324; SPTR: C1XW95 CRISPR-associated RAMP protein, Csm4 family; TIGRFAM: CRISPR-associated RAMP protein, Csm4 family; TIGRFAM: CRISPR-associated RAMP protein, Csm4 family.
  
     0.764
ADH62618.1
CRISPR-associated RAMP protein, Csm5 family; COGs: COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537:IPR010173; KEGG: ttj:TTHB151 hypothetical protein; PFAM: protein of unknown function DUF324; SPTR: C1XW94 CRISPR-associated RAMP protein, Csm5 family; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family.
  
     0.761
ADH62614.1
CRISPR-associated protein, Csm1 family; COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); InterPro IPR000160:IPR013408; KEGG: ttj:TTHB147 hypothetical protein; SPTR: C1XW98 CRISPR-associated protein, Csm1 family; TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: HD domain; TIGRFAM: CRISPR-associated protein, Csm1 family.
  
     0.757
ADH62599.1
OstA family protein; COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR005653; KEGG: ttj:TTHA0396 hypothetical protein; PFAM: OstA family protein; SPTR: C1XWB6 Putative uncharacterized protein.
  
     0.754
ADH62995.1
Hypothetical protein; KEGG: gbm:Gbem_1799 Fibronectin type III domain protein; SPTR: C1XXC0 Putative uncharacterized protein.
  
     0.751
ADH62806.1
Putative transmembrane anti-sigma factor; InterPro IPR018764; KEGG: ddr:Deide_3p01861 hypothetical protein; PFAM: Anti-sigma K factor RskA; SPTR: C1XSF1 Uncharacterized conserved protein (DUF2337); PFAM: Anti-sigma-K factor rskA.
  
     0.749
ADH62625.1
CRISPR-associated protein, TIGR02710 family; InterPro IPR014082; KEGG: ttj:TTHB144 hypothetical protein; PFAM: CRISPR-associated protein Cas02710; SPTR: C1XW86 CRISPR-associated protein, TIGR02710 family; TIGRFAM: CRISPR-associated protein, TIGR02710 family; PFAM: CRISPR-associated protein (Cas_Cas02710); TIGRFAM: CRISPR-associated protein, TIGR02710 family.
  
     0.738
ADH62621.1
CRISPR-associated protein Cas6; COGs: COG5551 conserved hypothetical protein; InterPro IPR010156:IPR019267; KEGG: ttj:TTHA0078 hypothetical protein; PFAM: Protein of unknown function DUF2276; SPTR: C1XW91 CRISPR-associated protein, Cas6 family; TIGRFAM: CRISPR-associated protein Cas6; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated protein Cas6.
  
     0.735
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.