STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADH64226.1Putative pilin, type IV; InterPro IPR012902:IPR001120; KEGG: dge:Dgeo_2110 putative pilin, type IV; SPTR: C1XPS3 Prepilin-type N-terminal cleavage/methylation domain-containing protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (148 aa)    
Predicted Functional Partners:
ADH64225.1
Putative pilin, type IV; InterPro IPR012902:IPR001120; KEGG: dge:Dgeo_2111 putative pilin, type IV; SPTR: C1XPS4 Prepilin-type N-terminal cleavage/methylation domain-containing protein; PFAM: Prokaryotic N-terminal methylation motif; Type II transport protein GspH; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; general secretion pathway protein H.
       0.837
ADH64227.1
InterPro IPR012902; KEGG: dra:DR_1234 hypothetical protein; SPTR: C1XPS2 Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
       0.837
ADH64224.1
Hypothetical protein; InterPro IPR015919; KEGG: gau:GAU_2472 hypothetical protein; SPTR: C1XPS7 Putative uncharacterized protein.
       0.836
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.746
ADH62516.1
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: ttj:TTHA0364 type IV pilus assembly protein PilF; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SPTR: C1XWL4 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain.
  
 
 0.662
ADH64229.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR003660:IPR003594:IPR009082:IPR 003661:IPR004358; KEGG: tth:TTC0388 sensory transduction protein kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C1XPS0 Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.632
ADH64007.1
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004:IPR001992:IPR018076; KEGG: ttj:TTHA0794 pilus assembly protein PilC; PFAM: Type II secretion system F domain; SPTR: C1XQG3 Type II secretory pathway, component PulF; PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F.
  
  
 0.619
ADH65015.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797:IPR004477:IPR001279; KEGG: ttj:TTHA1968 competence protein ComEC; PFAM: ComEC/Rec2-related protein; SMART: beta-lactamase domain protein; SPTR: C1XVB6 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein [...]
  
  
 0.604
ADH64223.1
KEGG: ttj:TTHA0721 hypothetical protein; SPTR: C1XPS8 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3108).
       0.538
ADH64230.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789:IPR011991:IPR011006; KEGG: tth:TTC0668 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: C1XPR9 Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
  
    0.503
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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