STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH64266.1Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: nca:Noca_3921 aminotransferase; PFAM: aminotransferase class-III; SPTR: C1XPN3 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)    
Predicted Functional Partners:
ADH64824.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: scl:sce0016 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: C1XV33 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.973
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.967
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR004639:IPR015421; KEGG: dra:DR_0555 glutamate-1-semialdehyde aminotransferase; PFAM: aminotransferase class-III; SPTR: C1XV37 Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.
  
  
 
0.922
ADH64265.1
GCN5-related N-acetyltransferase; InterPro IPR000182:IPR016181; KEGG: cvi:CV_0230 aminoglycoside N6'-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: C1XPN4 Acetyltransferase (GNAT) family protein; PFAM: Acetyltransferase (GNAT) family.
 
    0.790
ADH64264.1
Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR011059:IPR013108; KEGG: sti:Sthe_1513 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: C1XPN5 Predicted TIM-barrel fold metal-dependent hydrolase, COG1574; PFAM: Amidohydrolase family.
       0.766
ADH64263.1
Conserved hypothetical protein; InterPro IPR000182:IPR016181; KEGG: rca:Rcas_0119 hypothetical protein; SPTR: C1XPN6 Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family.
  
    0.758
ADH64262.1
Extracellular solute-binding protein family 1; COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR001188:IPR006059; KEGG: dba:Dbac_2005 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: C1XPN7 Spermidine/putrescine-binding periplasmic protein; PFAM: Bacterial extracellular solute-binding protein.
       0.709
ADH64822.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.660
ADH62294.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.608
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.583
Your Current Organism:
Meiothermus silvanus
NCBI taxonomy Id: 526227
Other names: M. silvanus DSM 9946, Meiothermus silvanus ATCC 700542, Meiothermus silvanus DSM 9946, Meiothermus silvanus VI-R2, Meiothermus silvanus str. DSM 9946, Meiothermus silvanus strain DSM 9946
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