STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)    
Predicted Functional Partners:
LOC106516630
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.983
mdh2
Malate dehydrogenase.
  
 0.982
me2
Malic enzyme.
   
 0.978
LOC106523960
Malic enzyme.
   
 0.978
me1
Malic enzyme.
   
 0.978
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.977
LOC106515651
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.969
LOC106523632
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.969
ldhb
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.969
LOC106526126
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.967
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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