STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106522315Disco-interacting protein 2 homolog C-like. (1383 aa)    
Predicted Functional Partners:
aasdh
acyl-CoA synthetase family member 4.
  
 0.741
ranbp2
E3 SUMO-protein ligase RanBP2.
   
 0.694
hsdl2
Hydroxysteroid dehydrogenase-like protein 2 isoform X1.
  
 0.663
palb2
Partner and localizer of BRCA2.
  
 0.646
ndufab1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.646
med14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 0.585
nup93
Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.
   
 0.585
med23
Mediator of RNA polymerase II transcription subunit 23.
    
 0.579
nup205
Nuclear pore complex protein Nup205.
   
 0.577
nup155
Nuclear pore complex protein Nup155.
   
 0.557
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
Server load: low (20%) [HD]