STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aph1aGamma-secretase subunit APH-1A. (258 aa)    
Predicted Functional Partners:
psenen
Gamma-secretase subunit PEN-2.
   
 0.996
ncstn
Nicastrin isoform X1.
   
 0.996
LOC106532604
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.992
LOC106535157
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 0.992
LOC106516268
Neurogenic locus notch homolog protein 1-like.
    
 0.863
LOC106528756
Neurogenic locus notch homolog protein 1-like.
    
 0.863
notch2
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.
    
 0.716
LOC106527096
Neurogenic locus notch homolog protein 2-like.
    
 0.716
LOC106512921
Retinol dehydrogenase 7-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.644
LOC106523944
Amyloid beta A4 protein-like.
    
 0.577
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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