STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
igf1rTyrosine-protein kinase receptor. (1406 aa)    
Predicted Functional Partners:
LOC106529800
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.972
LOC106536859
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.972
LOC106519158
Insulin receptor substrate 2-like isoform X1.
   
 0.962
LOC106523934
Insulin receptor substrate 2-like.
   
 0.962
LOC106524457
Insulin receptor substrate 2-B-like.
   
 0.959
LOC106529184
Insulin receptor substrate 1-B-like.
   
 0.959
LOC106523871
Growth factor receptor-bound protein 2.
   
 0.951
LOC106514242
Growth factor receptor-bound protein 10-like.
    
 0.949
LOC106518097
Growth factor receptor-bound protein 10-like isoform X1.
    
 0.949
ctnnb1
Catenin beta-1.
   
 0.928
Your Current Organism:
Austrofundulus limnaeus
NCBI taxonomy Id: 52670
Other names: A. limnaeus
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