node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKC35125.1 | SKC46733.1 | SAMN04324258_0104 | SAMN04324258_1065 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin-like domain; Manually curated. | 0.898 |
SKC35125.1 | SKC72717.1 | SAMN04324258_0104 | SAMN04324258_3206 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.474 |
SKC35125.1 | nrdI | SAMN04324258_0104 | SAMN04324258_0105 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Protein involved in ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.999 |
SKC35125.1 | ribBA | SAMN04324258_0104 | SAMN04324258_2820 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.853 |
SKC41251.1 | SKC46733.1 | SAMN04324258_0792 | SAMN04324258_1065 | Hypothetical protein. | Glutaredoxin-like domain; Manually curated. | 0.443 |
SKC41251.1 | ribBA | SAMN04324258_0792 | SAMN04324258_2820 | Hypothetical protein. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.409 |
SKC46727.1 | SKC46733.1 | SAMN04324258_1064 | SAMN04324258_1065 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Glutaredoxin-like domain; Manually curated. | 0.641 |
SKC46727.1 | SKC72717.1 | SAMN04324258_1064 | SAMN04324258_3206 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.764 |
SKC46727.1 | rex | SAMN04324258_1064 | SAMN04324258_1066 | HAD-superfamily subfamily IB hydrolase, TIGR01490. | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.610 |
SKC46733.1 | SKC35125.1 | SAMN04324258_1065 | SAMN04324258_0104 | Glutaredoxin-like domain; Manually curated. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.898 |
SKC46733.1 | SKC41251.1 | SAMN04324258_1065 | SAMN04324258_0792 | Glutaredoxin-like domain; Manually curated. | Hypothetical protein. | 0.443 |
SKC46733.1 | SKC46727.1 | SAMN04324258_1065 | SAMN04324258_1064 | Glutaredoxin-like domain; Manually curated. | HAD-superfamily subfamily IB hydrolase, TIGR01490. | 0.641 |
SKC46733.1 | SKC68813.1 | SAMN04324258_1065 | SAMN04324258_2622 | Glutaredoxin-like domain; Manually curated. | Protein of unknown function. | 0.420 |
SKC46733.1 | SKC70875.1 | SAMN04324258_1065 | SAMN04324258_2837 | Glutaredoxin-like domain; Manually curated. | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 0.459 |
SKC46733.1 | SKC72717.1 | SAMN04324258_1065 | SAMN04324258_3206 | Glutaredoxin-like domain; Manually curated. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.672 |
SKC46733.1 | msrA | SAMN04324258_1065 | SAMN04324258_0326 | Glutaredoxin-like domain; Manually curated. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.703 |
SKC46733.1 | nrdI | SAMN04324258_1065 | SAMN04324258_0105 | Glutaredoxin-like domain; Manually curated. | Protein involved in ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.534 |
SKC46733.1 | rex | SAMN04324258_1065 | SAMN04324258_1066 | Glutaredoxin-like domain; Manually curated. | Redox-sensing transcriptional repressor; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.772 |
SKC46733.1 | ribBA | SAMN04324258_1065 | SAMN04324258_2820 | Glutaredoxin-like domain; Manually curated. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.708 |
SKC68813.1 | SKC46733.1 | SAMN04324258_2622 | SAMN04324258_1065 | Protein of unknown function. | Glutaredoxin-like domain; Manually curated. | 0.420 |