SKC80898.1 protein (Krasilnikoviella flava) - STRING interaction network

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second shell of interactors

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Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SKC80898.1

Transmembrane secretion effector. (438 aa)

Predicted Functional Partners:

SKC58951.1

0.574

SKC52881.1

0.562

SKC51218.1

0.430

SKC80899.1

0.420

Your Current Organism:

Krasilnikoviella flava

NCBI taxonomy Id: 526729
Other names: CC 0387, CC0387, CCTCC AA208024, DSM 21481, JCM 16551, K. flava, Krasilnikoviella flava (Jiang et al. 2009) Nishijima et al. 2017, Promicromonospora flava, Promicromonospora flava Jiang et al. 2009, Promicromonospora sp. CC 0387

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SKC51218.1	SKC80898.1	SAMN04324258_1427	SAMN04324258_4118	Predicted arabinose efflux permease, MFS family.	Transmembrane secretion effector.	0.430
SKC52881.1	SKC58951.1	SAMN04324258_1580	SAMN04324258_1848	MFS transporter, DHA3 family, macrolide efflux protein.	Major Facilitator Superfamily protein.	0.698
SKC52881.1	SKC80898.1	SAMN04324258_1580	SAMN04324258_4118	MFS transporter, DHA3 family, macrolide efflux protein.	Transmembrane secretion effector.	0.562
SKC58951.1	SKC52881.1	SAMN04324258_1848	SAMN04324258_1580	Major Facilitator Superfamily protein.	MFS transporter, DHA3 family, macrolide efflux protein.	0.698
SKC58951.1	SKC80898.1	SAMN04324258_1848	SAMN04324258_4118	Major Facilitator Superfamily protein.	Transmembrane secretion effector.	0.574
SKC80898.1	SKC51218.1	SAMN04324258_4118	SAMN04324258_1427	Transmembrane secretion effector.	Predicted arabinose efflux permease, MFS family.	0.430
SKC80898.1	SKC52881.1	SAMN04324258_4118	SAMN04324258_1580	Transmembrane secretion effector.	MFS transporter, DHA3 family, macrolide efflux protein.	0.562
SKC80898.1	SKC58951.1	SAMN04324258_4118	SAMN04324258_1848	Transmembrane secretion effector.	Major Facilitator Superfamily protein.	0.574
SKC80898.1	SKC80899.1	SAMN04324258_4118	SAMN04324258_4119	Transmembrane secretion effector.	Hypothetical protein.	0.420
SKC80899.1	SKC80898.1	SAMN04324258_4119	SAMN04324258_4118	Hypothetical protein.	Transmembrane secretion effector.	0.420

Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.895

expected number of edges:

13

PPI enrichment p-value:

0.085

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006006

Glucose metabolic process

3 of 10

1.96

1.4

0.0017

GO:0005996

Monosaccharide metabolic process

4 of 29

1.62

1.3

0.0014

GO:0006090

Pyruvate metabolic process

3 of 15

1.78

1.18

0.0040

GO:0006091

Generation of precursor metabolites and energy

5 of 77

1.29

1.08

0.0014

GO:0006098

Pentose-phosphate shunt

2 of 3

2.3

1.06

0.0111

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016861

Intramolecular oxidoreductase activity, interconverting aldoses and ketoses

3 of 12

1.88

1.09

0.0073

GO:0016903

Oxidoreductase activity, acting on the aldehyde or oxo group of donors

3 of 22

1.61

0.93

0.0121

GO:0016853

Isomerase activity

4 of 75

1.21

0.76

0.0131

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:622

Pentose phosphate pathway, and Glyceraldehyde-3-phosphate dehydrogenase, type I

8 of 20

2.08

5.04

1.05e-12

CL:649

Pentose phosphate pathway

4 of 6

2.3

2.94

1.73e-06

CL:426

Mixed, incl. Carbon metabolism, and Fatty acid metabolism

11 of 148

1.35

2.43

1.05e-12

CL:623

Glycolysis, and Glyceraldehyde-3-phosphate dehydrogenase, type I

4 of 13

1.97

2.28

1.66e-05

CL:626

Glycolysis

2 of 6

2.0

0.84

0.0264

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00030

Pentose phosphate pathway

7 of 22

1.98

4.31

3.12e-11

map01200

Carbon metabolism

11 of 86

1.59

3.68

8.75e-16

map00010

Glycolysis / Gluconeogenesis

5 of 42

1.55

2.02

3.91e-06

map01230

Biosynthesis of amino acids

8 of 130

1.27

1.81

2.55e-08

map01120

Microbial metabolism in diverse environments

11 of 248

1.13

1.64

3.12e-11

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0312

Gluconeogenesis

2 of 4

2.18

0.99

0.0145

KW-0413

Isomerase

4 of 59

1.31

0.9

0.0069

KW-0324

Glycolysis

2 of 9

1.83

0.76

0.0352

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF17147

Pyruvate:ferredoxin oxidoreductase core domain II

2 of 2

2.48

0.84

0.0300

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029061

Thiamin diphosphate-binding fold

4 of 11

2.04

1.98

0.00011

IPR009014

Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II

3 of 7

2.11

1.41

0.0020

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00861

Transketolase, pyrimidine binding domain

2 of 6

2.0

0.82

0.0281

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