rnhB protein (Acetobacterium wieringae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rnhB

Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (259 aa)

Predicted Functional Partners:

dnaN

0.958

pksJ

0.954

rnhA

0.879

pgcA

0.867

sipT

0.843

ACWI_00390

0.840

thyA1

0.834

qorB

0.812

rbgA

0.811

polA_1

0.790

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_00390	rbgA	ACWI_00390	ACWI_00370	Hypothetical protein; Belongs to the UPF0102 family.	Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.608
ACWI_00390	rnhB	ACWI_00390	ACWI_00380	Hypothetical protein; Belongs to the UPF0102 family.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.840
ACWI_00390	sipT	ACWI_00390	ACWI_00360	Hypothetical protein; Belongs to the UPF0102 family.	Signal peptidase I T; Belongs to the peptidase S26 family.	0.590
dnaN	pksJ	ACWI_13190	ACWI_26840	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Polyketide synthase PksJ.	0.665
dnaN	polA_1	ACWI_13190	ACWI_00110	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.998
dnaN	rnhA	ACWI_13190	ACWI_27720	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.640
dnaN	rnhB	ACWI_13190	ACWI_00380	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.958
dnaN	thyA1	ACWI_13190	ACWI_28560	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Thymidylate synthase 1.	0.856
pgcA	pksJ	ACWI_23390	ACWI_26840	Phosphoglucomutase.	Polyketide synthase PksJ.	0.776
pgcA	rnhA	ACWI_23390	ACWI_27720	Phosphoglucomutase.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.450
pgcA	rnhB	ACWI_23390	ACWI_00380	Phosphoglucomutase.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.867
pksJ	dnaN	ACWI_26840	ACWI_13190	Polyketide synthase PksJ.	DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.665
pksJ	pgcA	ACWI_26840	ACWI_23390	Polyketide synthase PksJ.	Phosphoglucomutase.	0.776
pksJ	polA_1	ACWI_26840	ACWI_00110	Polyketide synthase PksJ.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.866
pksJ	qorB	ACWI_26840	ACWI_04160	Polyketide synthase PksJ.	Quinone oxidoreductase 2.	0.994
pksJ	rbgA	ACWI_26840	ACWI_00370	Polyketide synthase PksJ.	Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.864
pksJ	rnhA	ACWI_26840	ACWI_27720	Polyketide synthase PksJ.	Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.585
pksJ	rnhB	ACWI_26840	ACWI_00380	Polyketide synthase PksJ.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.954
pksJ	sipT	ACWI_26840	ACWI_00360	Polyketide synthase PksJ.	Signal peptidase I T; Belongs to the peptidase S26 family.	0.479
pksJ	thyA1	ACWI_26840	ACWI_28560	Polyketide synthase PksJ.	Thymidylate synthase 1.	0.467