ugd_1 protein (Acetobacterium wieringae) - STRING interaction network

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Score

ugd_1

UDP-glucose 6-dehydrogenase. (388 aa)

Predicted Functional Partners:

rffG_1

0.978

gtaB

0.960

rmlA

0.958

galE

0.912

tuaD

0.900

glmU

0.835

rmlC

0.795

rffG_2

0.742

pksJ

0.704

tuaB

0.672

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
galE	glmU	ACWI_12150	ACWI_01460	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.870
galE	gtaB	ACWI_12150	ACWI_23400	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.945
galE	pksJ	ACWI_12150	ACWI_26840	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Polyketide synthase PksJ.	0.615
galE	rffG_2	ACWI_12150	ACWI_23340	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	dTDP-glucose 4,6-dehydratase 2; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.546
galE	rmlA	ACWI_12150	ACWI_23360	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.846
galE	tuaD	ACWI_12150	ACWI_23410	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-glucose 6-dehydrogenase TuaD.	0.912
galE	ugd_1	ACWI_12150	ACWI_00550	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-glucose 6-dehydrogenase.	0.912
glmU	galE	ACWI_01460	ACWI_12150	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.870
glmU	gtaB	ACWI_01460	ACWI_23400	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UTP--glucose-1-phosphate uridylyltransferase.	0.905
glmU	pksJ	ACWI_01460	ACWI_26840	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Polyketide synthase PksJ.	0.501
glmU	rmlA	ACWI_01460	ACWI_23360	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.857
glmU	tuaD	ACWI_01460	ACWI_23410	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-glucose 6-dehydrogenase TuaD.	0.835
glmU	ugd_1	ACWI_01460	ACWI_00550	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-glucose 6-dehydrogenase.	0.835
gtaB	galE	ACWI_23400	ACWI_12150	UTP--glucose-1-phosphate uridylyltransferase.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.945
gtaB	glmU	ACWI_23400	ACWI_01460	UTP--glucose-1-phosphate uridylyltransferase.	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.905
gtaB	pksJ	ACWI_23400	ACWI_26840	UTP--glucose-1-phosphate uridylyltransferase.	Polyketide synthase PksJ.	0.472
gtaB	rffG_1	ACWI_23400	ACWI_00540	UTP--glucose-1-phosphate uridylyltransferase.	dTDP-glucose 4,6-dehydratase 2.	0.826
gtaB	rffG_2	ACWI_23400	ACWI_23340	UTP--glucose-1-phosphate uridylyltransferase.	dTDP-glucose 4,6-dehydratase 2; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.420
gtaB	rmlA	ACWI_23400	ACWI_23360	UTP--glucose-1-phosphate uridylyltransferase.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.928
gtaB	tuaD	ACWI_23400	ACWI_23410	UTP--glucose-1-phosphate uridylyltransferase.	UDP-glucose 6-dehydrogenase TuaD.	0.992