guaB protein (Acetobacterium wieringae) - STRING interaction network

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guaB

Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)

Predicted Functional Partners:

guaA_1

0.999

purA

0.985

purH

0.979

guaA_3

0.977

htpG

0.968

guaA_2

0.967

ribH

0.942

purL

0.942

ribBA

0.939

gltB_1

0.928

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
gltB_1	guaA_1	ACWI_09090	ACWI_01040	Ferredoxin-dependent glutamate synthase 1.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.939
gltB_1	guaA_2	ACWI_09090	ACWI_01920	Ferredoxin-dependent glutamate synthase 1.	GMP synthase.	0.745
gltB_1	guaA_3	ACWI_09090	ACWI_26920	Ferredoxin-dependent glutamate synthase 1.	GMP synthase.	0.779
gltB_1	guaB	ACWI_09090	ACWI_01050	Ferredoxin-dependent glutamate synthase 1.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.928
gltB_1	purA	ACWI_09090	ACWI_23780	Ferredoxin-dependent glutamate synthase 1.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.686
gltB_1	purH	ACWI_09090	ACWI_28150	Ferredoxin-dependent glutamate synthase 1.	Bifunctional purine biosynthesis protein PurH.	0.821
gltB_1	purL	ACWI_09090	ACWI_28210	Ferredoxin-dependent glutamate synthase 1.	Phosphoribosylformylglycinamidine synthase.	0.869
gltB_1	ribBA	ACWI_09090	ACWI_12870	Ferredoxin-dependent glutamate synthase 1.	Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.420
guaA_1	gltB_1	ACWI_01040	ACWI_09090	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ferredoxin-dependent glutamate synthase 1.	0.939
guaA_1	guaA_2	ACWI_01040	ACWI_01920	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GMP synthase.	0.733
guaA_1	guaA_3	ACWI_01040	ACWI_26920	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GMP synthase.	0.818
guaA_1	guaB	ACWI_01040	ACWI_01050	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA_1	htpG	ACWI_01040	ACWI_00840	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.422
guaA_1	purA	ACWI_01040	ACWI_23780	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.960
guaA_1	purH	ACWI_01040	ACWI_28150	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional purine biosynthesis protein PurH.	0.935
guaA_1	purL	ACWI_01040	ACWI_28210	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Phosphoribosylformylglycinamidine synthase.	0.993
guaA_1	ribBA	ACWI_01040	ACWI_12870	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.794
guaA_2	gltB_1	ACWI_01920	ACWI_09090	GMP synthase.	Ferredoxin-dependent glutamate synthase 1.	0.745
guaA_2	guaA_1	ACWI_01920	ACWI_01040	GMP synthase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.733
guaA_2	guaB	ACWI_01920	ACWI_01050	GMP synthase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.967

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