nadE protein (Acetobacterium wieringae) - STRING interaction network

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nadE

Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (648 aa)

Predicted Functional Partners:

nadD

0.959

pksJ

0.933

sfrB_1

0.919

sfrB_2

0.919

cinA_3

0.919

nadK

0.907

pncB2

0.894

cobB_2

0.888

ACWI_34660

0.881

gltB_1

0.863

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACWI_34660	cinA_3	ACWI_34660	ACWI_29250	Hypothetical protein.	Putative competence-damage inducible protein; Belongs to the CinA family.	0.662
ACWI_34660	nadD	ACWI_34660	ACWI_21490	Hypothetical protein.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.632
ACWI_34660	nadE	ACWI_34660	ACWI_01190	Hypothetical protein.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.881
ACWI_34660	nadK	ACWI_34660	ACWI_11800	Hypothetical protein.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.558
ACWI_34660	pksJ	ACWI_34660	ACWI_26840	Hypothetical protein.	Polyketide synthase PksJ.	0.607
ACWI_34660	pncB2	ACWI_34660	ACWI_23560	Hypothetical protein.	Nicotinate phosphoribosyltransferase pncB2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.635
cinA_3	ACWI_34660	ACWI_29250	ACWI_34660	Putative competence-damage inducible protein; Belongs to the CinA family.	Hypothetical protein.	0.662
cinA_3	cobB_2	ACWI_29250	ACWI_17900	Putative competence-damage inducible protein; Belongs to the CinA family.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	0.662
cinA_3	nadD	ACWI_29250	ACWI_21490	Putative competence-damage inducible protein; Belongs to the CinA family.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.944
cinA_3	nadE	ACWI_29250	ACWI_01190	Putative competence-damage inducible protein; Belongs to the CinA family.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.919
cinA_3	nadK	ACWI_29250	ACWI_11800	Putative competence-damage inducible protein; Belongs to the CinA family.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.721
cinA_3	pksJ	ACWI_29250	ACWI_26840	Putative competence-damage inducible protein; Belongs to the CinA family.	Polyketide synthase PksJ.	0.470
cinA_3	pncB2	ACWI_29250	ACWI_23560	Putative competence-damage inducible protein; Belongs to the CinA family.	Nicotinate phosphoribosyltransferase pncB2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.919
cobB_2	cinA_3	ACWI_17900	ACWI_29250	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Putative competence-damage inducible protein; Belongs to the CinA family.	0.662
cobB_2	nadD	ACWI_17900	ACWI_21490	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).	0.813
cobB_2	nadE	ACWI_17900	ACWI_01190	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.888
cobB_2	nadK	ACWI_17900	ACWI_11800	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.775
cobB_2	pksJ	ACWI_17900	ACWI_26840	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Polyketide synthase PksJ.	0.607
cobB_2	pncB2	ACWI_17900	ACWI_23560	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.	Nicotinate phosphoribosyltransferase pncB2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.635
gltB_1	nadE	ACWI_09090	ACWI_01190	Ferredoxin-dependent glutamate synthase 1.	Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.863

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