Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiKSirohydrochlorin cobaltochelatase. (263 aa)    
Predicted Functional Partners:
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.999
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase.
  
 0.994
ACWI_01720
Cobalamin biosynthesis protein CbiG.
 
  
 0.986
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
 
  
 0.966
cobK_1
precorrin-6A reductase.
 
  
 0.945
sirC
Precorrin-2 dehydrogenase.
    
 0.938
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.911
cobK_2
precorrin-6A reductase.
 
  
 0.877
cbiC
cobalt-precorrin-8X methylmutase.
 
  
 0.875
nasF
uroporphyrinogen-III C-methyltransferase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
   
 0.854
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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