STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hacAHomoaconitase large subunit. (640 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Belongs to the citrate synthase family.
 
 0.994
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.956
echA8
Putative enoyl-CoA hydratase echA8; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.925
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.907
hicd
Homoisocitrate dehydrogenase.
 0.904
rpmB
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.904
nifJ
Pyruvate-flavodoxin oxidoreductase.
    
 0.897
rpmA
50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.896
rpmJ
50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.894
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.891
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.