| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carA | carB | ACWI_23770 | ACWI_23760 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
| carA | glmS | ACWI_23770 | ACWI_04020 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.918 |
| carA | glnA_1 | ACWI_23770 | ACWI_23840 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Glutamine synthetase. | 0.948 |
| carA | glnA_2 | ACWI_23770 | ACWI_23860 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Glutamine synthetase. | 0.918 |
| carA | gltB_1 | ACWI_23770 | ACWI_09090 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Ferredoxin-dependent glutamate synthase 1. | 0.951 |
| carA | gltB_2 | ACWI_23770 | ACWI_09100 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Glutamate synthase [NADPH] small chain. | 0.907 |
| carA | purF | ACWI_23770 | ACWI_28180 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.976 |
| carB | carA | ACWI_23760 | ACWI_23770 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
| carB | glmS | ACWI_23760 | ACWI_04020 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.944 |
| carB | glnA_1 | ACWI_23760 | ACWI_23840 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamine synthetase. | 0.960 |
| carB | glnA_2 | ACWI_23760 | ACWI_23860 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamine synthetase. | 0.905 |
| carB | gltB_1 | ACWI_23760 | ACWI_09090 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Ferredoxin-dependent glutamate synthase 1. | 0.979 |
| carB | gltB_2 | ACWI_23760 | ACWI_09100 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Glutamate synthase [NADPH] small chain. | 0.913 |
| carB | purF | ACWI_23760 | ACWI_28180 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.984 |
| glmM | glmS | ACWI_04010 | ACWI_04020 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.974 |
| glmM | glmU | ACWI_04010 | ACWI_01460 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.995 |
| glmS | carA | ACWI_04020 | ACWI_23770 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.918 |
| glmS | carB | ACWI_04020 | ACWI_23760 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.944 |
| glmS | glmM | ACWI_04020 | ACWI_04010 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.974 |
| glmS | glmU | ACWI_04020 | ACWI_01460 | Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.932 |