Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metH_2Methionine synthase. (209 aa)    
Predicted Functional Partners:
acsE_6
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.944
acsE_1
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
    0.867
acsE_5
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.833
acsE_12
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.812
acsE_4
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.805
acsE_13
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.735
acsE_3
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.730
acsE_10
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.730
acsE_11
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.697
acsE_8
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.691
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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