typA protein (Acetobacterium wieringae) - STRING interaction network

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[Homology]

Score

typA

GTP-binding protein TypA/BipA. (604 aa)

Predicted Functional Partners:

rpsI

0.826

guaA_1

0.773

rplM

0.746

tig

0.686

infC

0.681

rpmI

0.650

ychF

0.643

rplA

0.636

rpoB

0.628

trmD

0.626

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
guaA_1	infC	ACWI_01040	ACWI_21400	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.542
guaA_1	rplA	ACWI_01040	ACWI_32230	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.913
guaA_1	rplM	ACWI_01040	ACWI_05990	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.837
guaA_1	rpmI	ACWI_01040	ACWI_21390	GMP synthase; Catalyzes the synthesis of GMP from XMP.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.517
guaA_1	rpoB	ACWI_01040	ACWI_34230	GMP synthase; Catalyzes the synthesis of GMP from XMP.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.904
guaA_1	rpsI	ACWI_01040	ACWI_06000	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.663
guaA_1	tig	ACWI_01040	ACWI_18810	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.666
guaA_1	trmD	ACWI_01040	ACWI_00340	GMP synthase; Catalyzes the synthesis of GMP from XMP.	tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.770
guaA_1	typA	ACWI_01040	ACWI_06010	GMP synthase; Catalyzes the synthesis of GMP from XMP.	GTP-binding protein TypA/BipA.	0.773
guaA_1	ychF	ACWI_01040	ACWI_21460	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.	0.803
infC	guaA_1	ACWI_21400	ACWI_01040	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.542
infC	rplA	ACWI_21400	ACWI_32230	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.937
infC	rplM	ACWI_21400	ACWI_05990	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.971
infC	rpmI	ACWI_21400	ACWI_21390	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.985
infC	rpoB	ACWI_21400	ACWI_34230	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.689
infC	rpsI	ACWI_21400	ACWI_06000	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.951
infC	tig	ACWI_21400	ACWI_18810	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.730
infC	trmD	ACWI_21400	ACWI_00340	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.616
infC	typA	ACWI_21400	ACWI_06010	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	GTP-binding protein TypA/BipA.	0.681
rplA	guaA_1	ACWI_32230	ACWI_01040	50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.913