| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | murAB | ACWI_12830 | ACWI_08780 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.487 |
| birA | murB | ACWI_12830 | ACWI_07000 | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.835 |
| ddlA | ftsQ | ACWI_02930 | ACWI_17740 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein FtsQ; Essential cell division protein. | 0.748 |
| ddlA | murAB | ACWI_02930 | ACWI_08780 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.611 |
| ddlA | murB | ACWI_02930 | ACWI_07000 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.988 |
| ddlA | murC | ACWI_02930 | ACWI_01490 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.984 |
| ddlA | murD_2 | ACWI_02930 | ACWI_17770 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.960 |
| ddlA | murE | ACWI_02930 | ACWI_11080 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. | 0.710 |
| ddlA | murF | ACWI_02930 | ACWI_17790 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
| ddlA | murG_1 | ACWI_02930 | ACWI_17750 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.861 |
| ddlA | spoVD | ACWI_02930 | ACWI_17800 | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Stage V sporulation protein D. | 0.763 |
| ftsQ | ddlA | ACWI_17740 | ACWI_02930 | Cell division protein FtsQ; Essential cell division protein. | D-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.748 |
| ftsQ | murB | ACWI_17740 | ACWI_07000 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.791 |
| ftsQ | murC | ACWI_17740 | ACWI_01490 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.914 |
| ftsQ | murD_2 | ACWI_17740 | ACWI_17770 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.974 |
| ftsQ | murE | ACWI_17740 | ACWI_11080 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. | 0.638 |
| ftsQ | murF | ACWI_17740 | ACWI_17790 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.925 |
| ftsQ | murG_1 | ACWI_17740 | ACWI_17750 | Cell division protein FtsQ; Essential cell division protein. | UDP-N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.968 |
| ftsQ | spoVD | ACWI_17740 | ACWI_17800 | Cell division protein FtsQ; Essential cell division protein. | Stage V sporulation protein D. | 0.987 |
| murAB | birA | ACWI_08780 | ACWI_12830 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.487 |