leuA_3 protein (Acetobacterium wieringae) - STRING interaction network

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leuA_3

2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (269 aa)

Predicted Functional Partners:

leuA_2

0.995

accC

0.950

nifJ

0.934

accA

0.931

leuA_1

0.922

leuA_5

0.922

leuA_4

0.920

korA

0.913

pdhC_1

0.911

pdhC_2

0.911

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
accA	accC	ACWI_29870	ACWI_29850	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	0.999
accA	korA	ACWI_29870	ACWI_17140	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-oxoglutarate oxidoreductase subunit KorA.	0.900
accA	leuA_1	ACWI_29870	ACWI_02570	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.931
accA	leuA_2	ACWI_29870	ACWI_08670	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-isopropylmalate synthase.	0.931
accA	leuA_3	ACWI_29870	ACWI_08680	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.931
accA	leuA_4	ACWI_29870	ACWI_12340	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.	0.931
accA	leuA_5	ACWI_29870	ACWI_12350	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.931
accA	nifJ	ACWI_29870	ACWI_08270	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Pyruvate-flavodoxin oxidoreductase.	0.918
accA	pdhC_1	ACWI_29870	ACWI_01060	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.679
accA	pdhC_2	ACWI_29870	ACWI_06690	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.679
accC	accA	ACWI_29850	ACWI_29870	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.	0.999
accC	korA	ACWI_29850	ACWI_17140	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-oxoglutarate oxidoreductase subunit KorA.	0.933
accC	leuA_1	ACWI_29850	ACWI_02570	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.950
accC	leuA_2	ACWI_29850	ACWI_08670	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-isopropylmalate synthase.	0.950
accC	leuA_3	ACWI_29850	ACWI_08680	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.950
accC	leuA_4	ACWI_29850	ACWI_12340	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.	0.950
accC	leuA_5	ACWI_29850	ACWI_12350	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.950
accC	nifJ	ACWI_29850	ACWI_08270	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Pyruvate-flavodoxin oxidoreductase.	0.952
accC	pdhC_1	ACWI_29850	ACWI_01060	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.731
accC	pdhC_2	ACWI_29850	ACWI_06690	Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.	0.731