Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lytR_1Sensory transduction protein LytR. (244 aa)    
Predicted Functional Partners:
ACWI_09150
Sensory histidine kinase DcuS.
 
  
 0.936
ypdA_1
Sensor histidine kinase YpdA.
 
 
 0.909
ypdA_2
Sensor histidine kinase YpdA.
 
  
 0.842
ACWI_27820
Sensory histidine kinase DcuS.
 
  
 0.675
ACWI_17380
Sensory histidine kinase DcuS.
 
  
 0.665
ACWI_31400
Sensory histidine kinase DcuS.
 
  
 0.582
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.539
aroG
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
       0.517
ACWI_09170
Methylcobalamin:coenzyme M methyltransferase; Belongs to the uroporphyrinogen decarboxylase family.
       0.442
ACWI_15310
Hypothetical protein.
   
    0.406
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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