Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dhaS_1HTH-type dhaKLM operon transcriptional activator DhaS. (182 aa)    
Predicted Functional Partners:
ACWI_14600
Hypothetical protein.
  
     0.531
ACWI_02340
Hypothetical protein.
  
     0.503
pksJ
Polyketide synthase PksJ.
     
 0.454
ACWI_13650
Oleate hydratase.
 
   
 0.449
ACWI_32570
Hypothetical protein.
  
     0.441
fucO
Lactaldehyde reductase.
       0.439
ACWI_09250
Hypothetical protein.
     
 0.413
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.409
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: medium (44%) [HD]