Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cas9CRISPR-associated endonuclease Cas9. (114 aa)    
Predicted Functional Partners:
ACWI_10250
Hypothetical protein.
       0.773
traG
Conjugal transfer protein TraG.
   
 
 0.639
ACWI_10230
Hypothetical protein.
       0.529
iscU_1
Iron-sulfur cluster assembly scaffold protein IscU.
      
 0.522
ACWI_21150
acetyl-CoA decarbonylase/synthase complex subunit gamma.
      
 0.522
aplIM
Modification methylase AplI.
  
  
 0.490
ctfB
Butyrate--acetoacetate CoA-transferase subunit B.
      
 0.483
hsdM
Type I restriction enzyme EcoKI M protein.
     
 0.452
ACWI_03530
Phage terminase.
  
  
 0.438
ACWI_31330
Phage terminase.
  
  
 0.438
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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