Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACWI_11440Hypothetical protein. (334 aa)    
Predicted Functional Partners:
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
      0.664
hsdR_2
Type-1 restriction enzyme R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
    0.653
hsdR_3
Type I restriction enzyme R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
    0.653
ACWI_11350
EcoKI restriction-modification system protein HsdS.
  
    0.636
ACWI_17340
Type I restriction modification DNA specificity domain protein.
  
    0.636
ACWI_20500
Putative type-1 restriction enzyme specificity protein.
  
    0.636
ACWI_20830
Hypothetical protein.
  
    0.630
ACWI_11340
Putative type I restriction enzymeP M protein.
  
    0.613
hsdM
Type I restriction enzyme EcoKI M protein.
  
    0.613
ACWI_20480
Putative type I restriction enzymeP M protein.
  
    0.613
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.