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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttdAL(+)-tartrate dehydratase subunit alpha. (280 aa)    
Predicted Functional Partners:
fumA
Fumarate hydratase class I, aerobic.
 
 0.999
ACWI_17050
FMN-binding domain protein.
  
 
 0.932
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.902
tyrB
Aromatic-amino-acid aminotransferase.
    
  0.887
sfrB_1
NADPH-Fe(3+) oxidoreductase subunit beta.
    
 0.831
sfrB_2
NADPH-Fe(3+) oxidoreductase subunit beta.
    
 0.831
sfrB_3
NADPH-Fe(3+) oxidoreductase subunit beta.
    
 0.806
ACWI_00990
NAD-dependent malic enzyme.
  
 
 0.773
ACWI_15190
NAD-dependent malic enzyme.
  
 
 0.773
argH1
Argininosuccinate lyase 1.
    
 0.761
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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