galE protein (Acetobacterium wieringae) - STRING interaction network

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Score

galE

UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)

Predicted Functional Partners:

gtaB

0.945

ugd_1

0.912

tuaD

0.912

glmU

0.870

rmlA

0.846

pksJ

0.615

ppdK_1

0.598

epsJ_1

0.593

ccpN

0.584

wfgD

0.581

Your Current Organism:

Acetobacterium wieringae

NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ccpN	galE	ACWI_12120	ACWI_12150	Transcriptional repressor CcpN.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.584
ccpN	pksJ	ACWI_12120	ACWI_26840	Transcriptional repressor CcpN.	Polyketide synthase PksJ.	0.649
ccpN	ppdK_1	ACWI_12120	ACWI_12140	Transcriptional repressor CcpN.	Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.	0.865
epsJ_1	galE	ACWI_12590	ACWI_12150	Putative glycosyltransferase EpsJ.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.593
epsJ_1	pksJ	ACWI_12590	ACWI_26840	Putative glycosyltransferase EpsJ.	Polyketide synthase PksJ.	0.581
epsJ_1	rmlA	ACWI_12590	ACWI_23360	Putative glycosyltransferase EpsJ.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.518
galE	ccpN	ACWI_12150	ACWI_12120	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Transcriptional repressor CcpN.	0.584
galE	epsJ_1	ACWI_12150	ACWI_12590	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Putative glycosyltransferase EpsJ.	0.593
galE	glmU	ACWI_12150	ACWI_01460	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.870
galE	gtaB	ACWI_12150	ACWI_23400	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.945
galE	pksJ	ACWI_12150	ACWI_26840	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Polyketide synthase PksJ.	0.615
galE	ppdK_1	ACWI_12150	ACWI_12140	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.	0.598
galE	rmlA	ACWI_12150	ACWI_23360	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.846
galE	tuaD	ACWI_12150	ACWI_23410	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-glucose 6-dehydrogenase TuaD.	0.912
galE	ugd_1	ACWI_12150	ACWI_00550	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-glucose 6-dehydrogenase.	0.912
galE	wfgD	ACWI_12150	ACWI_26630	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-Glc:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-glucosyltransferase WfgD.	0.581
glmU	galE	ACWI_01460	ACWI_12150	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.870
glmU	gtaB	ACWI_01460	ACWI_23400	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UTP--glucose-1-phosphate uridylyltransferase.	0.905
glmU	pksJ	ACWI_01460	ACWI_26840	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Polyketide synthase PksJ.	0.501
glmU	rmlA	ACWI_01460	ACWI_23360	Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.857