Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACWI_12420Sortase family protein. (218 aa)    
Predicted Functional Partners:
ACWI_12430
Hypothetical protein.
       0.793
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor; Belongs to the 5'-nucleotidase family.
  
  
 0.725
ACWI_12410
Hypothetical protein.
       0.623
srtB
Sortase family protein.
 
   
 0.525
cap8A_2
Capsular polysaccharide type 8 biosynthesis protein cap8A.
     
 0.494
ywqD_2
Tyrosine-protein kinase YwqD.
     
 0.472
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.458
fruA
PTS system fructose-specific EIIABC component.
     
 0.433
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.421
patA
Peptidoglycan O-acetyltransferase; Belongs to the membrane-bound acyltransferase family.
      
 0.404
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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