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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikANickel-binding periplasmic protein precursor. (531 aa)    
Predicted Functional Partners:
nikB_1
Nickel transport system permease protein NikB.
 0.999
gsiD_1
Glutathione transport system permease protein GsiD.
 0.998
gsiA
Glutathione import ATP-binding protein GsiA.
 
 0.997
nikB_2
Nickel transport system permease protein NikB.
 0.996
nikE
Nickel import ATP-binding protein NikE.
 
 0.975
gsiC
Glutathione transport system permease protein GsiC.
 0.940
dppC
Dipeptide transport system permease protein DppC.
 0.937
oppD
Oligopeptide transport ATP-binding protein OppD.
 
 0.891
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.852
oppF_1
Oligopeptide transport ATP-binding protein OppF.
 
 0.829
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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