Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speA_1Arginine decarboxylase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (709 aa)    
Predicted Functional Partners:
ACWI_13470
Hypothetical protein.
       0.773
ACWI_13490
Hypothetical protein; PSP1 C-terminal conserved region.
  
    0.741
dnaX_1
DNA polymerase III subunit tau.
       0.726
mdeA_2
Methionine gamma-lyase.
 
   
 0.694
ACWI_14120
AAA domain (dynein-related subfamily).
  
 
 0.666
ACWI_02740
AAA domain (dynein-related subfamily).
  
 
 0.662
speB
Agmatinase; Belongs to the arginase family.
 
   
 0.559
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
  
 0.542
trxA_1
Thioredoxin-1; Belongs to the thioredoxin family.
       0.533
ACWI_13500
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
       0.520
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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