Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACWI_14130Vitamin B12 dependent methionine synthase, activation domain. (217 aa)    
Predicted Functional Partners:
ald
Alanine dehydrogenase.
       0.741
exuT_1
Hexuronate transporter.
       0.741
ACWI_14160
Hypothetical protein.
       0.741
cypM
Cypemycin methyltransferase.
       0.685
ACWI_14120
AAA domain (dynein-related subfamily).
     
 0.610
acsD
Corrinoid/iron-sulfur protein small subunit.
   
 
 0.575
acsC
Corrinoid/iron-sulfur protein large subunit.
   
 
 0.575
mdeA_1
Methionine gamma-lyase.
  
 
 0.547
mdeA_3
Methionine gamma-lyase.
  
 
 0.547
speH
S-adenosylmethionine decarboxylase proenzyme precursor; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
  
  
 0.542
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.