Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metH_12Methionine synthase. (222 aa)    
Predicted Functional Partners:
acsE_6
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.955
acsE_5
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.926
acsE_12
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.907
acsE_13
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.900
acsE_2
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.888
acsE_4
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.818
acsE_7
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase.
 
    0.558
deoC1
Deoxyribose-phosphate aldolase 1; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
   0.469
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
   0.469
ACWI_14580
Acetyltransferase (GNAT) family protein.
       0.431
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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