node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fcl | gadB | ACWI_12500 | ACWI_09610 | GDP-L-fucose synthase. | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | 0.422 |
fcl | novP | ACWI_12500 | ACWI_15220 | GDP-L-fucose synthase. | Demethyldecarbamoylnovobiocin O-methyltransferase. | 0.479 |
fcl | pksJ | ACWI_12500 | ACWI_26840 | GDP-L-fucose synthase. | Polyketide synthase PksJ. | 0.943 |
fcl | rmlD | ACWI_12500 | ACWI_12530 | GDP-L-fucose synthase. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.840 |
gadB | fcl | ACWI_09610 | ACWI_12500 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | GDP-L-fucose synthase. | 0.422 |
gadB | glyA | ACWI_09610 | ACWI_35470 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.533 |
gadB | novP | ACWI_09610 | ACWI_15220 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Demethyldecarbamoylnovobiocin O-methyltransferase. | 0.481 |
gadB | pksJ | ACWI_09610 | ACWI_26840 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | Polyketide synthase PksJ. | 0.923 |
gadB | rffG_1 | ACWI_09610 | ACWI_00540 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | dTDP-glucose 4,6-dehydratase 2. | 0.422 |
gadB | rmlD | ACWI_09610 | ACWI_12530 | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.422 |
glyA | gadB | ACWI_35470 | ACWI_09610 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | 0.533 |
glyA | novP | ACWI_35470 | ACWI_15220 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Demethyldecarbamoylnovobiocin O-methyltransferase. | 0.485 |
glyA | pksJ | ACWI_35470 | ACWI_26840 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Polyketide synthase PksJ. | 0.879 |
glyA | pspA_1 | ACWI_35470 | ACWI_15230 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase 1. | 0.602 |
mocA_1 | novP | ACWI_15210 | ACWI_15220 | Molybdenum cofactor cytidylyltransferase. | Demethyldecarbamoylnovobiocin O-methyltransferase. | 0.503 |
mocA_1 | pspA_1 | ACWI_15210 | ACWI_15230 | Molybdenum cofactor cytidylyltransferase. | Phosphoserine phosphatase 1. | 0.657 |
novP | fcl | ACWI_15220 | ACWI_12500 | Demethyldecarbamoylnovobiocin O-methyltransferase. | GDP-L-fucose synthase. | 0.479 |
novP | gadB | ACWI_15220 | ACWI_09610 | Demethyldecarbamoylnovobiocin O-methyltransferase. | Glutamate decarboxylase; Belongs to the group II decarboxylase family. | 0.481 |
novP | glyA | ACWI_15220 | ACWI_35470 | Demethyldecarbamoylnovobiocin O-methyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.485 |
novP | mocA_1 | ACWI_15220 | ACWI_15210 | Demethyldecarbamoylnovobiocin O-methyltransferase. | Molybdenum cofactor cytidylyltransferase. | 0.503 |