Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ACWI_15720Pyridoxal phosphate (PLP) phosphatase. (442 aa)    
Predicted Functional Partners:
ACWI_15730
Hypothetical protein.
       0.773
gltB_1
Ferredoxin-dependent glutamate synthase 1.
       0.506
slyA_1
Transcriptional regulator SlyA.
       0.485
ACWI_15700
FMN-binding domain protein.
  
    0.468
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
       0.459
pflA_2
Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
       0.459
ACWI_25420
Bacterial Ig-like domain (group 2).
  
     0.409
ACWI_00710
Hypothetical protein.
  
     0.405
ACWI_25300
Hypothetical protein.
  
     0.404
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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