STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (283 aa)    
Predicted Functional Partners:
speD
S-adenosylmethionine decarboxylase proenzyme precursor; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
 
 0.998
speA_2
Arginine decarboxylase.
 
 0.998
speH
S-adenosylmethionine decarboxylase proenzyme precursor; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
 
 0.996
speB
Agmatinase; Belongs to the arginase family.
 
 
 0.991
ACWI_09270
2-oxoglutaramate amidase.
 
 
 0.933
nspC
Carboxynorspermidine/carboxyspermidine decarboxylase.
  
 0.932
fliM
Flagellar motor switch protein FliM.
    
   0.855
ACWI_16260
Carboxynorspermidine synthase.
    
 0.852
mtnP
S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
 
 
 0.826
speA_1
Arginine decarboxylase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
 0.778
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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