STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rebMdemethylrebeccamycin-D-glucose O-methyltransferase. (191 aa)    
Predicted Functional Partners:
pksJ
Polyketide synthase PksJ.
 
  
 0.932
speD
S-adenosylmethionine decarboxylase proenzyme precursor; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
    
  0.571
paaI
Acyl-coenzyme A thioesterase PaaI.
     
 0.567
gcvT_1
Aminomethyltransferase.
    
 0.564
bioB
Biotin synthase.
  
 
 0.562
gshAB_1
Glutathione biosynthesis bifunctional protein GshAB; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
 
 0.555
gshAB_2
Glutathione biosynthesis bifunctional protein GshAB.
  
 
 0.555
ACWI_16260
Carboxynorspermidine synthase.
     
 0.539
pfs
Aminodeoxyfutalosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
  
 0.516
nspC
Carboxynorspermidine/carboxyspermidine decarboxylase.
  
    0.515
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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