Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
paaIAcyl-coenzyme A thioesterase PaaI. (129 aa)    
Predicted Functional Partners:
lgrD
Linear gramicidin synthase subunit D; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.883
pksJ
Polyketide synthase PksJ.
  
 
 0.849
ACWI_03920
Phenylacetate-coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
  
 0.722
ACWI_22450
Phenylacetate-coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
  
 0.720
paaK
Phenylacetate-coenzyme A ligase.
 
  
 0.719
plsX
Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.697
ACWI_27000
Phenylacetate-coenzyme A ligase.
 
  
 0.689
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
  
 0.648
cca
CCA-adding enzyme.
   
   0.646
nspC
Carboxynorspermidine/carboxyspermidine decarboxylase.
  
  
 0.634
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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